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The emerging role of MIF in septic shock and infection

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Biotherapy

Abstract

The protein mediator described originally as macrophage migration inhibitory factor (MIF) has been “re-discovered” recently to be both a novel pituitary hormone and a pro-inflammatory, macrophage-derived cytokine. Emerging studies indicate that MIF plays a pivotal role not only in endotoxic shock but also in the host response to a variety of acute and chronic infections.

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Abbreviations

MIF:

Macrophage migration Inhibitory Factor

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Authors and Affiliations

  1. The Picower Institute for Medical Research, 11030, Manhassett, New York, USA

    Jürgen Bernhagen, Thierry Calandra & Richard Bucala

Authors
  1. Jürgen Bernhagen
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  2. Thierry Calandra
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  3. Richard Bucala
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Bernhagen, J., Calandra, T. & Bucala, R. The emerging role of MIF in septic shock and infection. Biotherapy 8, 123–127 (1994). https://doi.org/10.1007/BF01878495

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  • DOI: https://doi.org/10.1007/BF01878495

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