Summary
Eleven schizophrenics (7 females) displaying an acute psychotic episode received the partial dopamine agonist terguride in doses up to 2 mg per day. Improvement in terms of positive symptoms reduction was observed in two cases only. In contrast, in a previous clinical trial targeted at negative schizophrenic symptoms, the majority of the patients appeared to have benefited from terguride application.
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Olbrich, R., Schanz, H. An evaluation of the partial dopamine agonist terguride regarding positive symptoms reduction in schizophrenics. J. Neural Transmission 84, 233–236 (1991). https://doi.org/10.1007/BF01244973
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DOI: https://doi.org/10.1007/BF01244973