Summary
With refinements of quantitative histochemistry, i.e. oilwell technique, enzymaticP ianalysis and NADP/NADPH cycling an enzymatic polarization of the tubular epithelial cell from the rat nephron to NaKATPase can be established. NaKATPase activity is limited to the basal area of the epithelial cell. Brush border fragments lack NaKATPase activity.
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Schmidt, U., Dubach, U.C., Bieder, I. et al. NaK stimulated adenosinetriphosphatase: Intracellular localisation within the proximal tubule of the rat nephron. Pflugers Arch. 330, 265–270 (1971). https://doi.org/10.1007/BF00588617
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DOI: https://doi.org/10.1007/BF00588617