Abstract
One property common to all drugs that are abused is that they act on the central nervous system to produce feelings that are deemed desirable. Along with producing these so-called desirable effects, however, the drugs produce many other effects. These may be due to indirect actions resulting from the fact that all systems interact, or they may be due to the presence of specific receptors for a particular drug in many parts of the body. Receptors may be defined as chemical structures that first bind the drug and then produce an effect when they are activated. This definition is in contradistinction to a binding site or acceptor site, which binds the drug but does not produce a biological effect.
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Adler, M.W., Geller, E.B., Rogers, T.J., Henderson, E.E., Eisenstein, T.K. (1993). Opioids, Receptors, and Immunity. In: Friedman, H., Klein, T.W., Specter, S. (eds) Drugs of Abuse, Immunity, and AIDS. Advances in Experimental Medicine and Biology, vol 335. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2980-4_3
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