Regular ArticleSuperoxide Dismutase Mimetics
References (107)
- et al.
Superoxide dismutase: an enzymatic function for erythrocuprein
J Biol Chem
(1969) - et al.
Peroxynitrite formation from macrophage-derived nitric oxide
Arch Biochem Biophys
(1992) - et al.
Inactivation of human manganese-superoxide dismutase by peroxynitrite is caused by exclusive nitration of tyrosine 34 to 3-nitrotyrosine
J Biol Chem
(1998) - et al.
Tyrosine modifications and inactivation of active site manganese superoxide dismutase mutant (y34f) by peroxynitrite
Arch Biochem Biophys
(1999) - et al.
- et al.
Interstitial equilibration of superoxide dismutase correlates with it protective effect in the isolated rabbit heart
J Mol Cell Cardiol
(1991) Superoxide dismutase: rationale for use in reperfusion injury and inflammation
J Free Rad Biol Med
(1986)- et al.
Effect of superoxide dismutase derivative on cold-induced brain edema
Brain Res
(1989) - et al.
Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP
Exp Neurol
(2001) - et al.
Clastogenic factors in plasma of HIV-1 infected patients activate HIV-1 replication in vitro: inhibition by superoxide dismutase
Free Rad Biol Med
(1997)
Oxidative stress and neuro-aids: triggers, modulators and novel antioxidants
Trends Neurosci
Superoxide dismutase in development of obliterative bronchiolitis
Transplant Proc
Recombinant superoxide dismutase (SOD) administered by aerosol inhibits respiratory syncytial virus infection in cotton rats
Antiviral Res
Manganese superoxide dismutase overexpression attenuates MPTP toxicity
Neurobiol Dis
Successful treatment of radiation induced fibrosis using CuZn SOD an Mn SOD: an experimental study
Int J Radiat Oncol Biol Phys
Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice
Cell
Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death
Neuron
Metalloporphyrin class of therapeutic catalyic antioxidants
Tips
Free radicals in reperfusion-induced arrhythmias: study with EUK 8, a novel nonprotein catalytic antioxidant
Free Radic Biol Med
Effects of tempol, a membrane-permeable radical scavenger, in a rodent model of carrageenan-induced pleurisy
Eur J Pharmacol
Superoxide dismutase mimetics inhibit neutrophil-mediated human aortic endothelial cell injury in vitro
J Biol Chem
The formation of peroxynitrite in vivo from nitric oxide and superoxide
Chem Biol Interact
Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide
Febs Lett
DNA damage and oxidation of thiols peroxynitrite causes in rat thymocytes
Arch Biochem Biophys
Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthase in carrageenan-induced models of local inflammation
Eur J Pharmacol
Role of O2− in neutrophil recruitment into sites of dermal and pulmonary vasculitis
Free Rad Biol Med
Comparison of the cardiovascular effects of two novel superoxide dismutase mimetics, SC-55858 and SC-54417, in conscious dogs
Eur J Pharmacol
Is oxidative stress central to the pathogenesis of chronic obstructive pulmonary disease?
Trends Molec Medicine
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
Nat Genet
Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia
Proc Natl Acad Sci USA
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
Nat Genet
Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide-deficient mice
Proc Natl Acad Sci USA
Mitochondrial disease in superoxide dismutase 2 mutant mice
Proc Natl Acad Sci USA
Superoxide dimutase (SOD) and the PAF-antagonist (BN 52021) reduce small intestinal damage induced by ischemia-reperfusion
Free Rad Res Commun
Effects of antioxidants and PAF receptor antagonist in intestinal shock in the rat
Circ Shock
Superoxide dismutase and leupeptin prevent delayed reperfusion injury in the rat small intestine during burn shock
J Burn Care Rehab
A review: role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions
Am J Pathol
Hemorrhagic shock-induced bacterial translocation: The role of neutrophils and hydroxyl radicals
J Trauma
The induction of nitric oxide synthase and intestinal vascular permeability by endotoxin in the rat
Br J Pharmacol
Protective effects of a superoxide dismutase mimetic and peroxynitrite decomposition catalysts in endotoxin-induced intestinal damage
Br J Pharmacol
Inactivation of catecholamines by superoxide gives new insights on the pathogenesis of septic shock
Proc Natl Acad Sci USA
Mechanism of site-selective DNA nicking by the hydrodioxyl (perhydroxyl) radical
Biochemistry
Apparent hydroxyl radical production by peroxynitrite: implication for endothelial injury from nitric oxide and superoxide
Proc Natl Acad Sci USA
Pathological implications of nitric oxide, superoxide and peroxynitrite formation
Biochem Soc Trans
Peroxynitrite decomposition catalysts: Novel therapeutics for peroxynitrite-mediated pathology
Proc Natl Acad Sci USA
Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
Nature
Bioavailability of superoxide dismutase: implications for the anti-inflammatory action mechanism of orgotein
AAS
Superoxide dismutase for therapeutic use: clinical experience, dead ends and hopes
Mol Cell Biochem
Pharmacokinetics and safety of intravenous recombinant human superoxide dismutase (nk341) in healthy subjects
International Journal of Clinical Pharmacology and Therapeutics
Superoxide radical and superoxide dismutases
Ann Rev Biochem
Cited by (100)
Superoxide dismutase and neurological disorders
2024, IBRO Neuroscience ReportsManganese
2023, Encyclopedia of Human Nutrition: Volume 1-4, Fourth EditionThe neuroprotective role of morroniside against spinal cord injury in female rats
2021, Neurochemistry InternationalCitation Excerpt :GSH-PX can cause superoxide to undergo hydroxylation reaction to produce nontoxic hydroxyl compounds (Smallwood et al., 2018). SOD can cause oxygen free radicals to undergo disproportionation reactions (Salvemini et al., 2002). Thus, the antioxidant enzymes are capable of eliminating these harmful substances that are toxic (Borgstahl and Oberley-Deegan 2018).
Evaluation of the compounds commonly known as superoxide dismutase and catalase mimics in cellular models
2021, Journal of Inorganic BiochemistryCitation Excerpt :Indeed, to date, a huge diversity of manganese complexes has been reported for their ability to react catalytically with superoxide. They involved ligands such as salen derivatives [11–13], cyclic polyamine [14–19], tri- or dipodal nitrogen-centered ligands [20–24], 1,2-ethanediamine-centered ligands [25–27], desferrioxamine derivatives [15,28,29], polyaminocarboxylato- [30–32] or polycarboxylato ligands [33], peptides [34–36], porphyrins [37–42], phthalocyanines [43], texaphyrins [44,45], corroles [46–48] or biliverdin and its derivatives [49]. Some of these complexes have thus far been assayed on cellular [49–55] and in vivo models [9,53,56–65].
Effect of coordination dissymmetry on the catalytic activity of manganese catalase mimics
2020, Journal of Inorganic BiochemistryCitation Excerpt :In many pathological conditions and diseases, including cancer, neurological disorders, atherosclerosis, hypertension, ischemia/perfusion, diabetes, etc., the endogenous antioxidant systems can be overwhelmed. Administration of exogenous enzymes for the treatment of oxidative stress is limited by their short half-life, antigenicity, high cost, and large sizes that disable the enzymes to cross the cell membranes [3,4]. Therefore, low molecular weight enzyme mimics constitute an alternative to overcome these limitations [5–7], some of which have proven to protect cells from oxidative damage in animal models [8].
Preparation, characterization and activity of CuZn and Cu<inf>2</inf> superoxide dismutase mimics encapsulated in mesoporous silica
2020, Journal of Inorganic Biochemistry
- f1
Author for correspondence: Daniela Salvemini, MetaPhore Pharmaceuticals, 1910 Innerbelt Business Center Drive, St. Louis, Missouri 63114. Tel.: +1 314-426-4803; Fax: +1 314-426-7491, E-mail: [email protected]