PET occupancy of modafinil administered i.v. at various doses
Data shown are mean ± S.E.M. (n).
Drug | Dose | % DAT Occupancy ([11C]CFT) | % NET Occupancy ([11C]MeNER) |
|---|---|---|---|
| mg/kg | |||
| Modafinil | 2 | 6 ± 6 (2) | |
| Modafinil | 5 | 35 ± 12 (4) | 16 ± 7.8 (6) |
| Modafinil | 8 | 54 ± 2.96 (3) | 44 ± 12 (2) |
| Modafinil | 8 | [11C]Altropane: 67 (1) | |
| Methylphenidate | 0.3 | 51 ± 10 (2) |
|