TABLE 2

The effect of vehicle (saline) and ghrelin applied i.p. in a dose of 20 μg/kg on the MPO activity and MDA + 4HNE concentration in the gastric mucosa of intact rats and those subjected to I/R Mean ± S.E.M. of six to eight rats.


Type of Test

MPO Activity

MDA + 4HNE Content
ng / ml nmol / g
Intact 0.9 ± 0.06 4.4 ± 0.8
Vehicle 6.8 ± 0.16* 13.2 ± 2.8*
Ghrelin
2.9 ± 0.7
5.9 ± 1.1
  • * Significant change compared with the value in the intact gastric mucosa

  • Significant change compared with the value recorded in the vehicle-treated control rats