TABLE 4

Hepatic glutathione S-transferase (GST) activities in different subcellular fractions in wild type and RXRα KO mice using CDNB as substrate Data represent the mean ± S.D. (n = 5).


Genotype

GST Activity
Wild Type
RXRα KO
% of Control
μmol/mg
Cytosol 5.41 ± 0.9 2.59 ± 1.2*** 47.9
Mitochondria
0.27 ± 0.02
0.18 ± 0.02**
66.7
  • *** P < 0.001

  • ** P < 0.01, vs. wild type