TABLE 4
Calculated parameters [mean (±S.D.)] from rat PK study of RWJ-413216
Route
Dose
C
max
T
max
AUC(0-4 h)
t
½
mg/kg
ng/ml
h
ng/h/ml
h
Oral
a
30
162 (31)
3.3 (1.2)
436 (20)
NC
NC, not calculated.
↵
a
n
= 3