Ability of CPT-L2-BA3 to inhibit the growth of various human cancer cell lines
Cell Line | Cancer Type | IC50 |
|---|---|---|
| nM | ||
| CFPAC-1 | Pancreatic cancer | 625 |
| DMS-53 | Lung cancer | 828 |
| DU-145 | Prostate cancer | 240 |
| Hs746T | Gastric cancer | 821 |
| HT-29 | Colon cancer | 2269 |
| IMR32 | Neuroblastoma | 90 |
| LNCaP | Prostate cancer | 92 |
| MCF-7 | Breast cancer | 1705 |
| MOLT-4 | Leukemia | 33 |
| NCI-H69 | Lung cancer | 1923 |
| PC-3 | Prostate cancer | 198 |
| SKNSH | Neuroblastoma1610 | |
| U-87MG | Glioblastoma | 842 |
The ability of CPT-L2-BA3 to inhibit the proliferation of the human lung cancer cells was determined by the MTT assay. The mean value of eight determinations, IC50 (nanomolar), is shown. The S.E.M. was less than 10%.