TABLE 2
Inhibition of tumor proliferation in vivo
Nude mice bearing xenografts of the human tumor lines were injected twice a week with the indicated dose of CPT-L2-BA3. Subcutaneous injections were made in the flank opposite to the tumor implant. The tumor volume for animals treated with CPT-L2-BA3 was compared with that of animals injected with PBS. The mean value ± S.E.M. of 11 determinations is shown.