Effect of chronic ethanol consumption on the Emax and pD2 values for IRL1620 in endothelium-intact or -denuded carotid rings Values are means ± S.E.M. of n experiments.
Groups | Intact Endothelium | Denuded Endothelium | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Emax | pD2 | n | Emax | pD2 | n | |||||
| g | g | |||||||||
| Control | 0.041 ± 0.007 | 7.48 ± 0.13 | 9 | 0.065 ± 0.008a | 7.42 ± 0.13 | 11 | ||||
| Isocaloric | 0.035 ± 0.006 | 7.41 ± 0.11 | 6 | 0.060 ± 0.009a | 7.48 ± 0.22 | 6 | ||||
| Ethanol | 0.066 ± 0.008a | 7.53 ± 0.11 | 9 | 0.068 ± 0.007a | 7.35 ± 0.10 | 10 | ||||
↵ a Compared with control and isocaloric groups with intact endothelium (p < 0.05; ANOVA)