TABLE 3

Efficacy of A2M-PMB in protection of mice against polymicrobial infection

Dose/Time of Administration
No. Dead Mice/Total
Survival
%
Sham-operated mice 0/8 100
A2M-PMB: 250 μg/g; 30 min before CLP 3/8 63
PBSa; 30 min before CLP 8/8 0
Dextran-PMBb: 26 μg/g; 30 min before CLP
6/8
25

  • ↵ a Control mice were given 250 μ l of PBS intraperitoneally 30 min before CLP

  • ↵ b This amount is equivalent to 250 μ g/g A2M-PMB on basis of the PMB content