Drug effects on NGF immunoreactivity in the hippocampus Data are NGF (mean optical density ± S.E.M.)
Treatment | Region | ||||
|---|---|---|---|---|---|
| DG | CA1 | A3 | |||
| 7 Days | |||||
| VEH | 77.8 ± 5.3 | 60.8 ± 3.5 | 59.2 ± 3.8 | ||
| HAL | 108.2 ± 7.5** | 82.2 ± 5.1** | 81.0 ± 4.8** | ||
| ZIP | 105.8 ± 5.7** | 81.0 ± 4.9** | 80.0 ± 4.4** | ||
| 14 Days | |||||
| VEH | 75.5 ± 6.3 | 59.7 ± 3.9 | 58.8 ± 3.5 | ||
| HAL | 103.2 ± 6.5** | 80.8 ± 5.3** | 81.3 ± 5.7** | ||
| ZIP | 100.1 ± 4.9* | 79.9 ± 3.2** | 79.4 ± 4.5** | ||
| 45 Days | |||||
| VEH | 79.7 ± 5.8 | 61.5 ± 3.9 | 60.8 ± 4.1 | ||
| HAL | 58.2 ± 5.9* | 44.8 ± 3.2** | 35.3 ± 3.6*** | ||
| ZIP | 76.2 ± 5.1 | 60.4 ± 3.4 | 59.0 ± 3.4 | ||
| 90 Days | |||||
| VEH | 75.3 ± 3.3 | 58.1 ± 1.9 | 60.45 ± 2.2 | ||
| HAL | 32.4 ± 3.0*** | 24.8 ± 1.0*** | 29.2 ± 2.0*** | ||
| ZIP | 51.3 ± 1.9*** | 40.4 ± 1.3*** | 41.7 ± 2.5*** | ||