TABLE 1

Average number of injections

Monkey
FR
Cocaine
Remifentanil (μg / kg / inj)
Combination (Coc + Rem)
10
30
100
0.03
0.1
0.3
10 + 0.03
30 + 0.03
10 + 0.1
3511 10 107 152 48 155 172 94 170 117 174
32 44 64 33 74 123 77 164 80 154
100 17 20 24 20 39 50 33 72 49
320 2 8 16 1 5 15 4 7 7
1000 0 0 4 0 0 4 0 0 0
1780 0 0
2084 10 230 145 45 156 159 94 148 108 115
32 123 96 41 86 105 90 140 86 115
100 30 63 37 25 41 33 91 77 87
320 3 26 23 5 6 10 24 45 21
1000 0 1 10 0 0 0 1 3 5
1780 0 4 0 0 0
3593 10 164 207 145 142 160 113 219 200 208
32 121 106 113 97 106 82 152 162 161
100 30 39 50 41 59 53 73 93 72
320 11 21 27 7 11 16 4 26 21
1000 1 3 8 2 2 7 1 6 1
1780
0
5
0
2
1
2
0

  • Coc, cocaine; FR, fixed ratio; inj, injection; Rem, remifentanil