TABLE 1

Des-Arg9-bradykinin-induced paw rising in B1 WT and KO B1 mice in the absence or presence of LF22-0542



B1 WT

B1 KO

Mean(s) ± S.E.M.
n
Mean(s) ± S.E.M.
n
s s
Saline 8.0 ± 3.3 4 10.3 ± 4.4 5
Des-Arg9-bradykinin + vehicle 66.4 ± 9.9 5 11.0 ± 4.9 5
Des-Arg9-bradykinin + LF22–0542 (10 mg/kg s.c.)
15.3 ± 2.9
3
9.3 ± 3.5
3