Improvement in neurological behavior of dl-PHPB in rats after 2-h intraluminal suture occlusion of MCA and 24-h reperfusion
Values are mean ± S.E.M. (n = 10). dl-PHPB and dl-NBP were intravenously administered 10 min after the onset of MCAO.
Group | Neurological Score |
|---|---|
| Vehicle control | 3.2 ± 0.2## |
| dl-PHPB | |
| 1.3 mg/kg | 2.7 ± 0.1* |
| 3.9 mg/kg | 2.1 ± 0.2** |
| 12.9 mg/kg | 1.8 ± 0.2** |
| dl-NBP | |
| 10 mg/kg | 2.0 ± 0.2** |
| Sham-operated | 0.0 ± 0.0 |