Real-time RT-PCR confirmation of mRNA cytokine and chemokine up-regulation identified via microarray screening in J774A.1 macrophages treated with 100 μM z-VAD-fmk for 4 h versus DMSO-treated controls
Values are mean ± S.E.M.
Accession No. | Gene Name | Description | Total -Fold Up-Regulated |
|---|---|---|---|
| NM_008361 | IL1β | Interleukin 1β | 24 ± 4 |
| NM_013693 | TNFα | Tumor necrosis factor α | 6 ± 1 |
| NM_009140 | Cxcl2/Groβ | Chemokine (C-X-C motif) ligand 2 | 14 ± 2 |
| NM_011337 | Ccl3/MIP-1α | Chemokine (C-C motif) ligand 3 | 13 ± 1 |
| NM_013652 | Ccl4/MIP-1β | Chemokine (C-C motif) ligand 4 | 10 ± 2 |
| NM_013654 | Ccl7/MCP-3 | Chemokine (C-C motif) ligand 7 | 13 ± 2 |
| NM_021274 | Cxcl10/IP-10 | Chemokine (C-X-C motif) ligand 10 | 6 ± 1 |