Effect of selected diphenyl phosphine oxides on potassium currents in guinea pig ventricular myocytes
Currents measured with 3 μM DPO were compared with matched control currents and analyzed as described under Materials and Methods.
DPO No. | % Change at 3 μM | ||||
|---|---|---|---|---|---|
| IK1 | IKr | IKs | |||
| 1 | 15.0 ± 2.60 (n = 5)* | 3.0 ± 12.81 (n = 4) | 24.5 ± 4.60 (n = 5)* | ||
| 2 | 15.1 ± 1.5 (n = 6)* | 11.1 ± 11.2 (n = 6) | 12.2 ± 4.1 (n = 6)* | ||
↵* P < 0.05.