Group | Saline | SOV | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
12.5 mM (×1) | 12.5 mM (×2) | 25 mM | 37.5 mM | 50 mM | ||||||
Blood glucose (mg/dl) | ||||||||||
Pre-MCAO | 125 ± 18 | 125 ± 9 | 122 ± 9 | 127 ± 12 | 122 ± 12 | 122 ± 18 | ||||
45 Min post-MCAO | 128 ± 10 | 113 ± 6*,† | 110 ± 7*,† | 99 ± 6**,†† | 76 ± 5**,†† | 71 ± 8**,†† | ||||
90 Min post-MCAO | 136 ± 7 | 128 ± 6 | 95 ± 9**,†† | 122 ± 15 | 101 ± 10**,† | 76 ± 15**,† | ||||
Cerebral blood flow (%) | ||||||||||
Pre-MCAO | 100 | 100 | 100 | 100 | 100 | 100 | ||||
0 Min post-MCAO | 18 ± 19 | 18 ± 9 | 14 ± 12 | 19 ± 8 | 11 ± 10 | 14 ± 12 | ||||
45 Min post-MCAO | 50 ± 13 | 42 ± 20 | 43 ± 13 | 40 ± 9 | 39 ± 10 | 34 ± 14 | ||||
90 Min post-MCAO | 52 ± 11 | 42 ± 11 | 44 ± 14 | 38 ± 20 | 42 ± 8 | 33 ± 12* |