TABLE 1

Ability of S1P, its analogs, and other phospholipids to stimulate taurine efflux

Cells that had been prelabeled with [³H]taurine were washed with isotonic buffer A and then incubated in 230 mOsM buffer in the presence of the analogs at the concentrations indicated. Reactions were terminated after 5 min, and taurine efflux was monitored. Results are expressed as taurine efflux (percentage of total soluble radioactivity) and are the means ± S.E.M. for the number of separate experiments indicated. *, different from basal, P < 0.05, **, different from basal, P < 0.01.