TABLE 2

Ultrastructural documentation of gap junctions after ischemia/reperfusion in dogs treated with vehicle or rotigaptide


Group/Region

Photomicrographs with Gap Junctions Present/Photomicrographs Deemed Evaluable
Vehicle/infarct 2/19
Vehicle/border zone 2/17
Vehicle/area at risk 1/13
Vehicle/nonischemic 15/19
Rotigaptide/infarct 5/15
Rotigaptide/border zone 5/16
Rotigaptide/area at risk 10/22*
Rotigaptide/nonischemic
9/22
  • * Significantly differently higher than vehicle/area at risk (p = 0.022, Fisher's exact test).