TABLE 2

Intraluminal release of inflammatory mediators in rats with TNBS colitis treated with methylprednisolone and rolipram




PGE2

TXB2

LTB4
ng/ml pg/ml
Control 22 ± 3 8 ± 1.3 0.9 ± 0.2
Methylprednisolone 2 ± 0.4* 2 ± 0.4* 0.2 ± 0.1*
Rolipram
4 ± 0.3*
1 ± 0.2*
0.1 ± 0.1*
  • * p < 0.05 versus TNBS.