Parameters characterizing BS muscle cluster of contractions following different pharmacological treatments i.c.v. delivered
One-way analysis of variance followed by Student-Newman-Keuls test was used for intergroup comparisons. Raclopride- and spiperone-treated groups were not included in statistics.
Intracerebroventricular Treatment | Number of Clusters | Latency of First Cluster | Duration of Clusters | Intercluster Interval | Frequency of Bursts | ||
|---|---|---|---|---|---|---|---|
| s | s−1 | ||||||
| 8-OH-DPAT (20 μg) | +Saline | 3.14 ± 0.26† | 433 ± 92* | 17 ± 1 | 221 ± 38 | 0.58 ± 0.03 | |
| +WAY100635 (20 μg) | 2.20 ± 0.37† | 628 ± 91* | 19 ± 3 | 235 ± 41 | 0.48 ± 0.04 | ||
| +Raclopride (40 μg) | 1 | 568 | 14 | 0.51 | |||
| +β-Cyclodextrin 0.5% | 3.25 ± 0.63† | 722 ± 238† | 16 ± 3 | 315 ± 81 | |||
| +Spiperone (10 μg) | 0 | 0.63 ± 0.04 | |||||
| Quinelorane (20 μg) |
| 6.38 ± 0.75 | 98 ± 24 | 19 ± 1 | 226 ± 33 | 0.61 ± 0.04 | |