Basal acid secretion in wild-type and IP receptor knockout mice
Acid secretion was measured in wild-type and IP receptor knockout mice provided with an acute gastric fistula under urethane anesthesia. The stomach was filled with 0.4 ml of saline through the fistula, the solution was changed after 20 min, and the collected samples were used to measure acid output. Data are presented as the mean ± S.E.M. from four mice.
Group | No. of Mice | Total Acid Output |
|---|---|---|
| μEq/2 h | ||
| Wild-type mice | 4 | 3.01 ± 0.40 |
| IP knockout mice | 4 | 3.51 ± 0.43 |