An approximation of the IC50 values found for various cell lines
Experiments have been done in the same conditions as in Fig. 1. Each IC50 value was evaluated on four independent experiments.
A172 | HS683 | N2A | SH5Y | HCT116 | 293 | RDM4 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| μM | |||||||||||||
| Cisp | 3.9 ± 0.2 | 4.1 ± 0.1 | 3.3 ± 0.2 | 1-5 | 1-5 | 5.4 ± 1.1 | 1-5 | ||||||
| RDC-2 | >50 | >50 | >50 | >50 | >50 | >50 | >50 | ||||||
| RDC-3 | >50 | >50 | >50 | >50 | >50 | >50 | >50 | ||||||
| RDC-6 | 4.8 ± 0.2 | 3.2 ± 0.3 | 1-5 | 1-5 | 1-5 | 2.9 ± 0.3 | 5-15 | ||||||
| RDC-8 | >50 | >50 | >50 | >50 | >50 | >50 | >50 | ||||||
| RDC-9 | 1.7 ± 0.3 | 2.3 ± 0.2 | 1-5 | 1-5 | 1-5 | 4.1 ± 0.2 | 5-15 | ||||||
| RDC-10 | >50 | >50 | >50 | >50 | >50 | >50 | >50 | ||||||
| RDC-11 | 1.9 ± 0.2 | 3.1 ± 0.3 | 1-5 | 1-5 | 1-5 | 1-5 | 5-15 | ||||||
| RDC-12 | 12 ± 0.2 | 9.8 ± 1.1 | 15.1 ± 0.8 | 5-15 | 5-15 | 7.9 ± 0.2 | 5-15 | ||||||
Cisp, cisplatin.