Effects of intravenous pretreatment with SB-334867 (10 mg kg-1) 5 min before intravenous administration of orexin A (30 μg kg-1) on neurogenic dural vasodilation (n = 6)
Neurogenic Dural Vasodilation | Increase in Dural Vessel Diameter |
|---|---|
| % age change | |
| Control response | 131.1 ± 7 |
| 5 min post-SB-334867 | 132.6 ± 6 |
| 5 min postorexin A | 115.5 ± 7 |
| 15 min | 126.3 ± 9 |
| 30 min | 127.2 ± 7 |
| 45 min | 134.1 ± 10 |
| 60 min | 131.8 ± 6 |