Histopathology summary of tissues from mice treated with vehicle or O6-benzylguanine ± BCNU
Histopathological Finding | Vehicle | BCNU | O6-Benzylguanine (30 mg/kg) | ||||
|---|---|---|---|---|---|---|---|
| 15 mg/kg | 50 mg/kg | Alone | + BCNU (15 mg/kg) | ||||
| n | 2 | 2 | 5 | 2 | 5 | ||
| Lung | |||||||
| Cytomegaly | 0 | 1 | 5 | 0 | 5 | ||
| Alveolar edema w/alveolar histiocytosis | 0 | 0 | 2 | 0 | 1 | ||
| Alveolar histiocytosis alone | 0 | 0 | 3 | 1 | 3 | ||
| Liver | |||||||
| Cytomegaly | 0 | 0 | 5 | 0 | 0 | ||
| Extramedullary hematopoiesis | 0 | 0 | 0 | 0 | 2 | ||
| Kidney | |||||||
| Tubular atrophy | 0 | 0 | 5 | 0 | 0 | ||