Log of normalized ratios for metallopeptidases in oropharyngeal and kidney tissues
The relative gene expressions vs. controls of mAPP and NEP are normalized to GAPDH. Average ratios (n = 6) are expressed as mean ± S.D. Values are log means ± S.D. Only tissues with significant differences are shown (p < 0.05).
mAPP-Normalized Ratio (log) | ||||||
|---|---|---|---|---|---|---|
| Groups | Average | p Value vs. Control | ||||
| Tongue | LPS | -3.89 ± 0.14 | 0.567 | |||
| 7-day ACEi | -1.37 ± 0.62 | <0.001 | ||||
| One-time ACEi | -3.25 ± 0.41 | 0.883 | ||||
| Control | -3.48 ± 0.85 | |||||
| Laryngeal tissue | LPS | -1.28 ± 0.20 | 0.998 | |||
| 7-day ACEi | 0.06 ± 0.19 | 0.027 | ||||
| One-time ACEi | -1.19 ± 0.51 | 1.000 | ||||
|
| Control | -1.22 ± 1.09 |
| |||
| NEP-Normalized Ratio (log) | ||||||
|
| Groups | Average | p Value vs. Control | |||
| Kidney | LPS | 1.4 ± 0.15 | <0.001 | |||
| 7-day ACEi | 2.3 ± 0.25 | 0.038 | ||||
| One-time ACEi | 1.4 ± 0.05 | <0.001 | ||||
| Control | 2.0 ± 0.28 | |||||
| Tongue | LPS | 0.71 ± 0.18 | 0.295 | |||
| 7-day ACEi | 1.81 ± 0.51 | 0.007 | ||||
| One-time ACEi | 0.96 ± 0.19 | 0.955 | ||||
| Control | 1.04 ± 0.25 | |||||
| Parotid | LPS | 1.48 ± 0.64 | 0.780 | |||
| 7-day ACEi | 3.47 ± 0.37 | 0.026 | ||||
| One-time ACEi | 1.88 ± 1.16 | 1.000 | ||||
|
| Control | 1.87 ± 0.64 |
| |||