TABLE 2

Effect of incubation with serum or whole blood on the moment parameters for galactosylated lipoplex in the liver perfusion experiments Results are expressed as the mean ± S.D. of three experiments. Statistical comparisons with the no incubation group were performed by Dunnett's test.


Incubation

AUC

MRT

E
% of dose · s / ml s %
None (control) 62.0 ± 5.05 14.9 ± 1.03 87.0 ± 1.04
With serum 177 ± 13.9* 7.96 ± 0.56* 65.3 ± 1.94*
With whole blood
79.4 ± 2.43
18.6 ± 2.95
83.2 ± 1.22**
  • * P < 0.01

  • ** P < 0.05