TABLE 2

Assay table for inhibition of human phosphodiesterase enzymes The assays were performed using the following general procedures.


Assay

Origin

Reference Compound
Phosphodiesterase II (h) Differentiated U-937 cells EHNA
Phosphodiesterase III (h) Human platelets Milrinone
Phosphodiesterase IV (h) U-937 cells Rolipram
Phosphodiesterase V (h)
Human platelets
Dipyridamole
  • h, human; EHNA, erythro-9-(2-hydroxy-3-nonyl)adenine.