TABLE 1

Hemodynamics: Protocol 1 Values are reported as percentage of baseline (100%).



PreCO

Occlusion

Reperfusion

10 min
30 min
10 min
15 min
1 h
2 h
LV-Developed Pressure*
   Control 98±1 26±3 57±6 55±5 41±8
   PC 79±3 22±4 47±6 49±9 37±10
   d-myo-IP3 97±3 37±9 56±7 50±4 44±4
   l-myo-IP3 99±5 31±7 53±10 50±9 45±9
   XeC + Control 98±3 34±6 62±10 52±11 47±10
   XeC + d-myo-IP3 97±2 29±4 50±5 44±6 40±6
Coronary Flow
   Control 48±5 86±6 54±14
   PC 56±5 73±10 54±15
   d-myo-IP3 55±5 76±5 55±9
   l-myo-IP3 58±4 71±5 57±5
   XeC + Control 57±8 82±8 57±8
   XeC + d-myo-IP3

53±2

81±4


63±9
  • * p< 0.01 over time

  • p < 0.05 vs. control

  • p < 0.01 over time; no significant differences among groups