TABLE 2
BAB inhibition of Kv4.2 channels
K
D
and steady-state inhibition determined from data in
Fig. 8D
.
K
D
Inhibition
n
μ
M
%
Wild type
0.06 ± 0.01
35.0 ± 0.5
9
V397T
26.8 ± 6.0
30.8 ± 1.0
12
L400T
5.4 ± 3.5
6.1 ± 0.1
3
V404T
0.4 ± 0.2
24.5 ± 0.8
10