Baseline renal vascular resistance (mm Hg/ml/min/g kidney weight) in in vivo experiments
Values represent means ± S.E.M. for indicated n.
Period 1 | Period 2 | |
|---|---|---|
| No inhibitor | ||
| Time control (n = 11) | No UK: 22 ± 3 | No UK: 22 ± 2 |
| UK-14,304 (n = 12) | No UK: 21 ± 3 | Plus UK: 18 ± 2 |
| U-73122 | ||
| Time control (n = 7) | No UK: 20 ± 2 | No UK: 20 ± 1 |
| UK-14,304 (n = 7) | No UK: 22 ± 2 | Plus UK: 22 ± 2 |
| GF109203X | ||
| Time control (n = 8) | No UK: 20 ± 3 | No UK: 22 ± 3 |
| UK-14,304 (n = 8) | No UK: 19 ± 2 | Plus UK: 17 ± 1 |
| Wortmannin | ||
| Time control (n = 7) | No UK: 22 ± 3 | No UK: 22 ± 2 |
| UK-14,304 (n = 6) | No UK: 24 ± 3 | Plus UK: 20 ± 3 |
| CGP77675 | ||
| Time control (n = 7) | No UK: 18 ± 2 | No UK: 21 ± 3 |
| UK 14,304 (n = 6) | No UK: 20 ± 2 | Plus UK: 21 ± 4 |