TABLE 1

Morphologic data of hearts from sham-operated control and aortic-constricted rats Values are mean ± S.E.M.




Control (n = 36)

Control + TMZ (n = 34)

Hypertrophy (n = 33)

Hypertrophy + TMZ (n = 33)
Heart weight (g) 1.86 ± 0.02 1.86 ± 0.04 2.23 ± 0.04a,b 2.18 ± 0.04a,b
Body weight (g) 451 ± 5 456 ± 7 453 ± 10 451 ± 7
Heart weight/body weight (g/kg)
4.12 ± 0.04
4.09 ± 0.08
4.95 ± 0.09a,b
4.83 ± 0.05a,b
  • a Versus control, p < 0.05

  • b Versus control + TMZ, p < 0.05