TABLE 1

Effects of an insulin mimetic and a novel PPARγ agonist on adipose depot mass (in grams)

Retroperitoneal
Mesenteric
Gonadal
Subscapular
Control SHR 2.9 ± 0.2 1.8 ± 0.2 4.4 ± 1 <1
Control SHROB 18 ± 1 17 ± 1 22 ± 1.8 22 ± 1
PPEIA 26 ± 2* 16 ± 1 19 ± 0.9 28 ± 2*
DMAQ-B1
21 ± 1
15 ± 1
13 ± 0.7*
16 ± 1*

  • ↵* Significantly different from untreated control, p < 0.05 by t test