Selected COX-2-independent effects of coxibs relevant to cancer
Effect | Reference |
|---|---|
| Inhibition of cell proliferation | Badawi et al. (2004) |
| Induction of apoptosis | Ding et al. (2005) |
| Induction of cell cycle block | Maier et al. (2004) |
| Survivin expression | Teh et al. (2004) |
| Cytochrome c release | Sun et al. (2002) |
| NAG-1 induction | Yamaguchi et al. (2004) |
| Carbonic anhydrase inhibition | Weber et al. (2004) |
NAG-1, NSAID-activated gene 1.