TABLE 5

Results of morphometric analysis of liver sections of BDL rats with and without rapamycin treatment


Group

Volume Fraction
BDL CTR (n = 7)
BDL SIR (n = 11)
%
Hepatocytes 55.4 ± 12.2 76.2 ± 3.1*
Connective tissue 10.4 ± 4.4 5.0 ± 1.8*
Bile duct epithelial cells 18.3 ± 7.5 4.5 ± 3.7*
Desmin-positive cells 14.5 ± 3.4 7.4 ± 2.7*
Actin-positive cells 11.1 ± 7.6 3.1 ± 4.2*
Actin/desmin-positive cells
0.71 ± 0.37
0.34 ± 0.4*
  • * Statistically significant differences between BDL rapamycin-treated and non-treated rats (p < 0.05).