TABLE 3

Animal characteristics of sham-operated, BDL CTR, and BDL SIR rats


Treatment Group

Body Weight*

Liver Weight§

Spleen Weight#

AST+

Bilirubin**

Bile Acids++
g U/l μmol/l
Sham (n = 6) 303.8 ± 45 12.9 ± 2.9 0.8 ± 0.1 78.3 ± 8.7 84.1 ± 23.2 14.0 ± 8.5
BDL SIR (n = 8) 335.9 ± 28 20.3 ± 3.4 0.9 ± 0.1 92.6 ± 27.3 423.2 ± 167.0 58.2 ± 37.7
BDL CTR (n = 8)
362.1 ± 43.8
27 ± 5.8
2.3 ± 0.7
271.4 ± 79.0
1296.8 ± 868.1
279.5 ± 108.5
  • * p < 0.05 comparing BDL CTR rats with sham-operated rats; §p < 0.01 between all groups; #p < 0.001 comparing BDL SIR rats with BDL CTR rats and between BDL CTR rats and sham-operated animals; +p < 0.001 comparing BDL CTR with BDL SIR and sham-operated rats; **p < 0.01 comparing BDL CTR with BDL SIR and sham-operated rats; ++p < 0.001 comparing BDL CTR with BDL SIR and sham-operated rats.