Original Data Set | 1000 Bootstrap Replicates | |||||
---|---|---|---|---|---|---|
Estimate | CV | Estimate | CV | |||
% | % | |||||
Structural model | ||||||
CL, ml/min/kg | ||||||
Θintercept | 14 | 2.4 | 14 | 2.6 | ||
Θslope | 95 | 32 | 95 | 30 | ||
V1, ml/kg | ||||||
Θintercept | 120 | 7.6 | 113 | 7.4 | ||
Θslope | 2150 | 3.9 | 2080 | 3.9 | ||
V2, ml/kg | ||||||
Θintercept | 300 | 20 | 306 | 16 | ||
Θslope | 2900 | 5.3 | 2920 | 5.0 | ||
V3, ml/kg | ||||||
Θintercept | 810 | 13 | 812 | 14 | ||
Θslope | 3900 | 31 | 3960 | 34 | ||
Q2, ml/min | 26.0 | 18 | 27.0 | 20 | ||
Q3, ml/min | 7.3 | 30 | 7.28 | 31 | ||
Interanimal variability | ||||||
ωCL, % | 12 | 36 | 12 | 39 | ||
ωV1, % | 60 | 61 | 68 | 76 | ||
ωV2, % | 19 | 41 | 18 | 44 | ||
ωV3, % | 10 | 46 | 10 | 53 | ||
Residual variability | ||||||
Proportional error, % | 13 | 10 | 13 | 11 |