Blood β-galactosidase enzyme activity
Data are means ± S.E. Milliunits per milliliter of enzyme activity were converted into percentage of ID per milliliter based on the specific activity (milliunits per microgram) and the ID of the unconjugated β-gal or the β-gal-8D3 conjugate.
Dose | Units | β-Gal-8D3 at 1 h | β-Gal at 1 h | β-Gal-8D3 at 4 h | β-Gal at 4 h | Endogenous Activity |
|---|---|---|---|---|---|---|
| μg | ||||||
| 150 | mU/ml | 4879 ± 762 | 960 ± 35 | 493 ± 21 | 38 ± 9 | 4.3 ± 0.5 |
| %ID/ml | 4.1 ± 0.6 | 0.85 ± 0.04 | 0.41 ± 0.01 | 0.034 ± 0.008 | ||
| 15 | mU/ml | 939 ± 46 | 28 ± 2 | N.D. | N.D. | |
|
| %ID/ml | 8.0 ± 0.4 | 0.23 ± 0.02 | N.D. | N.D. |
|
N.D., not determined.