Group | Test Compounds | Dose | Number of rats | Route | Estrogen-Primed (2 μg/kg) | Uterine Weighta |
---|---|---|---|---|---|---|
mg/kg | mg | |||||
1 | CP8863 | 0 | 5 | p.o. | + | 186.4 ± 23.5 |
2 | 0.01 | 5 | p.o. | + | 163.8 ± 13.0 | |
3 | 0.1 | 5 | p.o. | + | 135.2 ± 20.1b | |
4 | 1.0 | 5 | p.o. | + | 148.1 ± 16.9b | |
5 | 10 | 5 | p.o. | + | 141.5 ± 10.9b | |
6 | 10 | 6 | p.o. | - | 54.5 ± 10.5 | |
7 | 0 | 6 | p.o. | - | 40.3 ± 6.9 | |
8 | MPA | 0 | 5 | p.o. | + | 174.4 ± 21.6 |
9 | 0.01 | 5 | p.o. | + | 165.9 ± 38.8 | |
10 | 0.1 | 5 | p.o. | + | 144.4 ± 7.7 | |
11 | 1.0 | 5 | p.o. | + | 95.0 ± 10.6b | |
12 | 10 | 5 | p.o. | + | 121.7 ± 10.8b | |
13 |
| 10 | 6 | p.o. | - | 85.6 ± 45.1c |