TABLE 2

5-HT2A and 5-HT2B receptor binding affinities determined using agonist radioligand displacement

The numbers in parentheses represent the number of independent experiments (n) used to determine the mean ± S.E.M.



Ki

5-HT2A
5-HT2B
nM
WAY-162545 136 ± 18 (3) 2101 ± 803 (3)
WAY-163909 212 ± 29 (7) 485 ± 49 (3)
WAY-163907
4766 ± 1406 (3)
>10,000 (3)