5-HT2C receptor binding affinities determined using agonist and antagonist radioligand displacement
The numbers in parentheses represent the number of independent experiments (n) used to determine the mean ± S.E.M.
Ki | |||
|---|---|---|---|
| [125I]DOI | [3H]Mesulergine | ||
| nM | |||
| WAY-162545 | 6.6 ± 0.5 (3) | 385 ± 112 (3) | |
| WAY-163909 | 10.5 ± 1.1 (8) | 221 ± 29 (8) | |
| WAY-163907 | 2021 ± 332 (5) | 10,351 ± 2318 (5) | |