Effect of inhibitors on the time for [Ca2+]i to return to basal values after addition of BK
Condition | Peak [Ca2+]i | Time to Return to Basal [Ca2+]i |
|---|---|---|
| nM | s | |
| BK (3 nM) | 302 ± 8 | 101 ± 5 |
| BK (100 nM) + U73122 | 256 ± 60 | 46 ± 5*** |
| BK (100 nM) + genistein | 231 ± 27 | 62 ± 5*** |
| BK (100 nM) + NiCl2 | 313 ± 30 | 55 ± 12*** |
| BK (100 nM) + EGTA | 229 ± 32 | 34 ± 4*** |
↵*** P < 0.001 compared with BK (3 nM).