Plasma lipoprotein profiles in the Ldlr-null mice fed ordinary diet (control) and high cholesterol diet supplemented with vehicle and 0.04 and 0.2% w/w cilostazol, respectively
Each value (milligrams per deciliter) represents mean ± S.E.M.
Group | Control | High Fat Diet | ||||
|---|---|---|---|---|---|---|
| Vehicle | Cilostazol (0.04%) | Cilostazol (0.2%) | ||||
| No. of animals | 6 | 6 | 6 | 6 | ||
| Total cholesterol | 346.7 ± 13.6 | 1835.0 ± 20.0### | 1787.8 ± 20.1 | 1820.8 ± 23.9 | ||
| HDL | 87.3 ± 4.3 | 13.0 ± 1.8### | 13.4 ± 1.8 | 15.9 ± 3.5 | ||
| LDL | 101.5 ± 6.4 | 500.0 ± 7.2### | 521.3 ± 9.7 | 476.3 ± 41.7 | ||
| Triglyceride | 60.7 ± 4.6 | 268.7 ± 92.1# | 86.0 ± 17.6 | 57.2 ± 11.3* | ||
↵# P < 0.05, ###P < 0.001 versus control; * P < 0.05 versus vehicle group.