Maximal contractile responses to noradrenaline in Ca2+-free medium in the arterial vasculature of young (6-week-old) and adult (16-week-old) WKY or SHR Values are expressed as a percentage of the contractile response to noradrenaline in Ca2+-containing medium (mean ± S.E.M.). Values in parentheses represent the number of experiments.
Young | Adult | ||||||
|---|---|---|---|---|---|---|---|
| WKY | SHR | WKY | SHR | ||||
| Aorta | Phasic | 27.3 ± 2.5 | 30.1 ± 7.8 | 33.9 ± 4.1 | 34.4 ± 4.0 | ||
| Tonic | 15.7 ± 3.4 | 18.0 ± 7.2 | 16.6 ± 1.7 | 17.6 ± 2.3 | |||
| (8) | (6) | (15) | (15) | ||||
| Iliac | Phasic | 1.1 ± 0.7 | 2.3 ± 0.8 | 9.4 ± 2.8† | 16.7 ± 2.2†† | ||
| Tonic | 6.5 ± 1.8 | ||||||
| (8) | (5) | (8) | (16) | ||||
| Tail | Phasic | 7.6 ± 2.7 | 11.3 ± 4.3 | 22.3 ± 3.4††† | 26.1 ± 2.4† | ||
| Tonic | 5.0 ± 1.1 | ||||||
| (6) | (3) | (7) | (9) | ||||
| Main mesenteric | Phasic | 22.8 ± 2.9 | 21.6 ± 3.0 | 18.2 ± 2.4 | 32.7 ± 3.0**† | ||
| Tonic | 3.5 ± 0.7 | 9.6 ± 2.7 | 5.3 ± 1.5 | 11.4 ± 1.3** | |||
| (7) | (9) | (14) | (17) | ||||
| SMA-1 | Phasic | 3.0 ± 1.9 | 9.7 ± 4.4* | 9.8 ± 1.9† | 31.5 ± 3.9***† | ||
| Tonic | 7.0 ± 1.4 | ||||||
| (6) | (3) | (10) | (11) | ||||
| SMA-2 | Phasic | 0.9 ± 0.6 | 5.9 ± 1.9* | 9.1 ± 2.2† | 19.5 ± 2.1**† | ||
| Tonic | 3.2 ± 0.4 | ||||||
|
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| (5) | (3) | (9) | (16) | ||