Pretreatment (24 h) | Log KA | Bmax | n |
---|---|---|---|
fmol/105 cells | |||
Vehicle | −9.73 ± 0.15 | 4.49 ± 0.94 | 6 |
100 μM CCh | −9.73 ± 0.05 | 1.34 ± 0.27** | 3 |
20 nM atropine | −9.79 ± 0.14 | 6.63 ± 0.17* | 3 |
20 μM gallamine | −9.69 ± 0.17 | 6.42 ± 0.07* | 4 |
Log KA, logarithm of the radioligand equilibrium dissociation constant; Bmax, maximal density of binding sites; n, number of experiments.
*p < 0.05, as determined by one-way ANOVA; **p < 0.01, as determined by one-way ANOVA.