TABLE 1

Systemic hemodynamic parameters at baseline


Baseline Hemodynamics

Control

GLP-1
n = 8 n = 6
LVP (mm Hg) 113 ± 4 114 ± 5
LVEDP (mm Hg) 12 ± 1 12 ± 1
LV dP/dt (mm Hg/s) 2355 ± 85 2295 ± 147
MAP (mm Hg) 85 ± 4 89 ± 4
HR (min-1) 74 ± 4 73 ± 6
CO (l/min) 1.9 ± 0.3 2 ± 0.4
CBF (ml/min) 21 ± 1 20 ± 2
PWTh (mm) 2.6 ± 0.3 2.6 ± 0.2
FS (%) 14 ± 1 15 ± 1
dL/dt (mm/s) 11.8 ± 1 11.3 ± 1
t1/2 (ms)
21.6 ± 0.7
21.9 ± 0.8
  • CO, cardiac output; HR, heart rate; LVP, left ventricular pressure, LVEDP, left ventricular end-diastolic pressure; LV dP/dt: first derivative of LVP during systole; MAP, mean arterial pressure; PWTh: posterior wall thickening.