TABLE 1

Relative rates of CBZ β-D-glucuronide formation by human tissue microsomes and cloned/expressed UGTs The control substrates used to confirm activity at a concentration of 2 mM. All values are within the normal range expected for these substrates (Gaiser et al., 2003). Morphine glucuronidation rates for human tissues were included to give a better indication of relative UGT2B7 levels, although it should be noted that morphine is not exclusively a UGT2B7 substrate.